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Autophagy as a molecular target for cancer treatment

11 Apr 2019

Abstract excerpt

Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells recycle or degrades internal constituents through membrane-trafficking pathway. Thus, autophagy provides the cells with a sustainable source of biomolecules and energy for the maintenance of homeostasis under stressful conditions such as tumor microenvironment. Recent findings revealed a close relationship between autophagy...

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PMID: 30981885
DOI: 10.1016/j.ejps.2019.04.011

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