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Article

Metabolomic profiling identifies pathways associated with minimal residual disease in childhood acute lymphoblastic leukaemia.

EBioMedicine - 1 Oct 2019

Schraw Jeremy M, Junco Jacob J, Brown Austin L, Scheurer Michael E, Rabin Karen R, Lupo Philip J

Abstract excerpt

BACKGROUND: End-induction minimal residual disease (MRD) is the strongest predictor of relapse in paediatric acute lymphoblastic leukaemia (ALL), but an understanding of the biological pathways underlying early treatment response remains elusive. We hypothesized that metabolomic profiling of diagnostic bone marrow plasma could provide insights into the underlying biology of early treatment response and inform...

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Identifiers

PMID: 31631039
DOI: 10.1016/j.ebiom.2019.09.033
PMCID: PMC6838385

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NAMPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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