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Article

Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosis

15 Oct 2019

Abstract excerpt

Previous work has reported the important links between cellular bioenergetics and the development of chronic kidney disease, highlighting the potential for targeting metabolic functions to regulate disease progression. More recently, it has been shown that alterations in fatty acid oxidation (FAO) can have an important impact on the progression of kidney disease. In this work, we demonstrate that loss of miR-33,...

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PMID: 31613798
DOI: 10.1172/jci.insight.131102

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