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Genetically Increased Telomere Length and Aging-Related Traits in the U.K. Biobank

11 Oct 2019

Abstract excerpt

Telomere length (TL) shortens over time in most human cell types and is a potential biomarker of aging. However, the causal association of TL on physical and cognitive traits that decline with age has not been extensively examined in middle-aged adults. Using a Mendelian randomization (MR) approach, we utilized genetically increased TL (GI-TL) to estimate the impact of TL on aging-related traits among U.K....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31603979
DOI: 10.1093/gerona/glz240

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