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Race, Natriuretic Peptides, and High-Carbohydrate Challenge

7 Oct 2019

Abstract excerpt

Rationale: Lower NP (natriuretic peptide) levels may contribute to the development of cardiometabolic diseases. Blacks have lower NP levels than middle-aged and older white adults. A high-carbohydrate challenge causes an upregulation of a negative ANP regulator microRNA-425 ( miR-425 ), which reduces ANP (atrial-NP) levels in whites. Objectives: We designed a prospective trial to study racial differences in (1)...

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PMID: 31588864
DOI: 10.1161/circresaha.119.315026

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