Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell–Intrinsic Transcriptional MSI Traits

4 Oct 2019

Abstract excerpt

Abstract Gastric cancer is the world's third leading cause of cancer mortality. In spite of significant therapeutic improvements, the clinical outcome for patients with advanced gastric cancer is poor; thus, the identification and validation of novel targets is extremely important from a clinical point of view. We generated a wide, multilevel platform of gastric cancer models, comprising 100 patient-derived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Gastric Cancer Management and Outcomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31585941
DOI: 10.1158/0008-5472.can-19-1166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell–Intrinsic Transcriptional MSI TraitsPMID 31585941Read ↗

Gastric Cancer in the Era of Precision MedicineSemantic proximity Read ↗

Divergent clonal evolution and tumor microenvironment remodeling shape gastric cancer peritoneal metastasis.Semantic proximity Read ↗

Deciphering of intra‐tumoural heterogeneity and the interplay between metastasis‐associated meta‐program and myofibroblasts in gastric cancerSemantic proximity Read ↗

Xenograft and organoid models in developing precision medicine for gastric cancer (Review)Semantic proximity Read ↗

Evaluation of molecular subtypes and clonal selection during establishment of patient-derived tumor xenografts from gastric adenocarcinomaSemantic proximity Read ↗

Molecular pathogenesis, targeted therapies, and future perspectives for gastric cancer.Semantic proximity Read ↗

Molecular Features and Translational Outlook for Epstein–Barr virus-associated Gastric CancerSemantic proximity Read ↗

Single-cell profiling of gastric cancer ascites reveals immunosuppressive remodeling and an epithelial-immune dual phenotype signature predictive for PD-1 immunotherapy responsesSemantic proximity Read ↗

Integrative single-cell and spatial transcriptomics uncover ELK4-mediated mechanisms in NDUFAB1+ tumor cells driving gastric cancer progression, metabolic reprogramming, and immune evasionSemantic proximity Read ↗

Molecular features and prognostic factors of locally advanced microsatellite instability-high gastric cancer.Semantic proximity Read ↗

Patient-Derived Gastric Carcinoma Xenograft Mouse Models Faithfully Represent Human Tumor Molecular DiversitySemantic proximity Read ↗

Spatially Resolved Niche and Tumor Microenvironmental Alterations in Gastric Cancer Peritoneal Metastases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.