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Article

Deciphering of intra‐tumoural heterogeneity and the interplay between metastasis‐associated meta‐program and myofibroblasts in gastric cancer

28 Apr 2025

Abstract excerpt

BACKGROUND: Gastric cancer (GC) exhibits high heterogeneity that relies on the oncogenic properties of cancer cells and multicellular interactions in the tumour microenvironment. However, the heterogeneity of GC and their molecular characteristics are still largely unexplored. METHODS: We employed single-cell and spatial transcriptomics to comprehensively map the intra-tumoural heterogeneity within GC....

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PMID: 40292733
DOI: 10.1002/ctm2.70319

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