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Molecular Features and Translational Outlook for Epstein–Barr virus-associated Gastric Cancer

24 Oct 2018

Abstract excerpt

Epstein–Barr virus (EBV) was the first discovered human tumor virus and is the etiological agent of B-cell lymphomas and also epithelial cancers. Indeed, nearly 10% of gastric cancers worldwide are EBV-positive and display unique molecular, epigenetic and clinicopathological features. EBV-positive gastric cancers display the highest rate of host genome methylation of all tumor types studied and harbor recurrent...

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PMID: 34367314
DOI: 10.2217/fvl-2018-0071

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