CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.

doi:10.1093/gerona/glz213

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Article

CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.

The journals of gerontology. Series A, Biological sciences and medical sciences - 16 Sept 2020

Kolicheski Ana, Walton Ronald L, Soto-Beasley Alexandra I, Heckman Michael G, Uitti Ryan J, Parfitt Francine, Graff-Radford Michelle R, Wszolek Zbigniew K, Graff-Radford Neill R, Ross Owen A

Abstract excerpt

A number of efforts are underway to better understand the role of genetic variation in successful aging and longevity. However, to date, only two genes have been consistently associated with longevity in humans: APOE and FOXO3, with the APOE ɛ2 allele also protective against dementia. Recently, using an exome-wide SNP array approach, a missense variant CLEC3B c.316G>A (rs13963 p.S106G) was reported to associate...

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Identifiers

PMID: 31570938
DOI: 10.1093/gerona/glz213
PMCID: PMC7494029

Genes

CLEC3B
APOE
FOXO3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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