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Article

Cutting Edge: Fetal/Placental Type I IFN Can Affect Maternal Survival and Fetal Viral Load during Viral Infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2017

Racicot Karen, Aldo Paulomi, El-Guindy Ayman, Kwon Ja-Young, Romero Roberto, Mor Gil

Abstract excerpt

Pregnant women have greater mortality and complications associated with viral infections compared with the general population, but the reason for the increased susceptibility is not well defined. Placenta type I IFN is an important immune modulator and protects the pregnancy. We hypothesized that loss of placental IFN affects the regulation of the maternal immune system, resulting in the differential response to...

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Identifiers

PMID: 28264970
DOI: 10.4049/jimmunol.1601824
PMCID: PMC5633930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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