Article

Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection

2022-09-02

Abstract excerpt

The immunological surveillance factors controlling vulnerability of the female reproductive tract (FRT) to sexually transmitted viral infections are not well understood. Interferon-epsilon (IFNε) is a distinct, immunoregulatory type-I IFN that is constitutively expressed by FRT epithelium and is not induced by pathogens like other antiviral IFNs α, β and λ. We show the necessity of IFNε for Zika Virus (ZIKV) prote...

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Literature Corpus work: 24b267fc-b4f5-50c8-bdea-c580d9580684
DOI: 10.1101/2022.09.01.505971

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