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Article

Modelling the long QT syndrome with induced pluripotent stem cells.

Nature - 10 Mar 2011

Itzhaki Ilanit, Maizels Leonid, Huber Irit, Zwi-Dantsis Limor, Caspi Oren, Winterstern Aaron, Feldman Oren, Gepstein Amira, Arbel Gil, Hammerman Haim, Boulos Monther, Gepstein Lior

Abstract excerpt

The ability to generate patient-specific human induced pluripotent stem cells (iPSCs) offers a new paradigm for modelling human disease and for individualizing drug testing. Congenital long QT syndrome (LQTS) is a familial arrhythmogenic syndrome characterized by abnormal ion channel function and sudden cardiac death. Here we report the development of a patient/disease-specific human iPSC line from a patient with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21240260
DOI: 10.1038/nature09747

Genes

KCNH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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