Article

Melatonin reduces cell motility and antioxidant defenses in ovarian cancer cell lines

2025-01-31

Abstract excerpt

<title>Abstract</title> <p>Ovarian cancer (OC), a highly recurrent and fatal tumor, poses diagnostic challenges due to generic symptoms and chemoresistance. Melatonin (Mel) is an indoleamine acting against tumor progression and exhibiting pro-oxidative actions in tumor cells. This study explores the impact of Mel on antioxidant defenses of OC cells (SKOV-3 and CAISMOV-24 lines), focusing on its receptor-dependent...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2fbce5f3-d0e2-5948-b085-2fe86b76e866
DOI: 10.21203/rs.3.rs-5924048/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Melatonin reduces cell motility and antioxidant defenses in ovarian cancer cell linesDOI 10.21203/rs.3.rs-5924048/v1Read

Melatonin and Cancer HallmarksSemantic proximity Read

Melatonin and andrographolide synergize to inhibit the colospheroid phenotype by targeting Wnt/beta-catenin signaling.Semantic proximity Read

Melatonin as Potential Targets for Delaying Ovarian AgingSemantic proximity Read

Nano-Based Drug Delivery and Targeting to Overcome Drug Resistance of Ovarian CancersSemantic proximity Read

Melatonin modulation of intracellular signaling pathways in hepatocarcinoma HepG2 cell line: role of the MT1 receptorSemantic proximity Read

Melatonin biosynthesis and regulation in reproductionSemantic proximity Read

Inhibition of Proliferation in Ovarian Cancer Cell Line (PA-1) By The Action of Green Compound ‘Betanin’Semantic proximity Read

PGC1α induced by reactive oxygen species contributes to chemoresistance of ovarian cancer cellsSemantic proximity Read

Melatonin Sensitize the Ovarian Cancer Cells to Cisplatin through suppression of PI3K/Akt pathwaySemantic proximity Read

Melatonin Increases the Anticancer Potential of Doxorubicin in Caco-2 Colorectal Cancer CellsSemantic proximity Read

Cancer metastasis: Mechanisms of inhibition by melatoninSemantic proximity Read

Revealing Melatonin’s Mysteries: Receptors, signaling pathways, and therapeutics applicationsSemantic proximity Read