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Silibinin Induces Apoptosis and Suppresses Cell Migration by Targeting the Transforming growth factor-β Signaling Pathway in Osteosarcoma Cells

2024-10-15

Abstract excerpt

<title>Abstract</title> <p>Osteosarcoma is the most common primary malignant bone tumor in children and teenagers, followed by lymphomas and brain tumors. Silibinin, a flavonolignan mix from milk thistle, has anticancer, neuroprotective, and anti-diabetic properties. It induces apoptosis in MG-63 cells.; Silibinin treatment of MG-63 cells resulted in a dose-dependent inhibition of cell viability; for the MG-63 ce...

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Literature Corpus work
31f132eb-e9c6-55ce-9a4a-a0ff270f205a
DOI
10.21203/rs.3.rs-4933548/v1
Open publication

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