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Article

Iron overload signature in chrysotile‐induced malignant mesothelioma

2 Aug 2012

Abstract excerpt

Exposure to asbestos is a risk for malignant mesothelioma (MM) in humans. Among the commercially used types of asbestos (chrysotile, crocidolite, and amosite), the carcinogenicity of chrysotile is not fully appreciated. Here, we show that all three asbestos types similarly induced MM in the rat peritoneal cavity and that chrysotile caused the earliest mesothelioma development with a high fraction of sarcomatoid...

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PMID: 22864872
DOI: 10.1002/path.4075

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