Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population‐Specific Patterns of Epigenetic Defects in the B Cell Lineage in Patients With Systemic Lupus Erythematosus

20 Aug 2019

Abstract excerpt

OBJECTIVE: To determine the stage of B cell development at which a systemic lupus erythematosus (SLE)-associated DNA methylation signature originates in African American (AA) and European American (EA) subjects, and to assess whether epigenetic defects in B cell development patterns could be predictive of SLE status in individual and mixed immune cell populations. METHODS: B cells from AA patients (n = 31) and EA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Systemic Lupus Erythematosus Research
Share to Systemic Sclerosis and Related Diseases
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31430064
DOI: 10.1002/art.41083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population‐Specific Patterns of Epigenetic Defects in the B Cell Lineage in Patients With Systemic Lupus ErythematosusPMID 31430064Read ↗

DNA Methylation Profiling in Childhood-Onset Lupus Reveals Distinct Epigenetic Clusters and Suggests Epigenetic Drivers of Disease ActivitySemantic proximity Read ↗

A Comprehensive Analysis of Type I Interferon Risk Gene Signatures in Systemic Lupus Erythematosus.Semantic proximity Read ↗

Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell PopulationsSemantic proximity Read ↗

Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical PracticeSemantic proximity Read ↗

DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneitySemantic proximity Read ↗

Differential regulation of the interferon response in systemic lupus erythematosus distinguishes patients of Asian ancestry.Semantic proximity Read ↗

Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: Identifying DNA methylation signatures associated with interferon-related genes based on ethnicity and SLEDAISemantic proximity Read ↗

Region- and variance-based DNA methylation analyses reveal novel disease genes and pathways for systemic lupus erythematosusSemantic proximity Read ↗

The Lupus Epigenome Relates to Genetics, Transcription and Serological Profiles with Dependency on Molecular Subtypes and Informs Drug DiscoverySemantic proximity Read ↗

Comprehensive Analysis of Epigenetic Modifications and Immune-Cell Infiltration In Tissues from Patients With Systemic Lupus ErythematosusSemantic proximity Read ↗

Single‐Cell Profiling of Bone Marrow B Cells and Early B Cell Developmental Disorders Associated With Systemic Lupus ErythematosusSemantic proximity Read ↗

Epigenetic programming underpins B cell dysfunction in human SLESemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.