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Article

Mass Cytometry Discovers Two Discrete Subsets of CD39−Treg Which Discriminate MGUS From Multiple Myeloma

2 Aug 2019

Abstract excerpt

Multiple Myeloma (MM) is preceded by the clinically stable condition monoclonal gammopathy of undetermined significance (MGUS), which is defined by the presence of a monoclonal protein and less than 10% malignant plasma cell infiltration in the bone marrow (BM). Critical immune events that discriminate MGUS from newly diagnosed MM (NDMM) patients remain unknown, but may involve changes in the regulatory T cell...

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PMID: 31428081
DOI: 10.3389/fimmu.2019.01596

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