Article
Myeloma skews regulatory T and pro-inflammatory T helper 17 cell balance in favor of a suppressive state.
Leukemia & lymphoma - 1 May 2014
Favaloro James, Brown Ross, Aklilu Esther, Yang Shihong, Suen Hayley, Hart Derek, Fromm Phillip, Gibson John, Khoo Liane, Ho P Joy, Joshua Douglas
Abstract excerpt
Abstract Discrepancies in the literature between regulatory T cell (Treg) and pro-inflammatory T helper 17 (Th17) numbers in multiple myeloma (MM) can be largely explained by technical differences in methodology and patient selection. In this study, Treg cells were defined as CD3(+)CD4(+)CD25(++)...
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