Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV Therapy

12 Jul 2019

Abstract excerpt

Currently, the most effective and durable therapeutic option for HIV-1 infection is combination antiretroviral therapy (cART). Although cART is powerful and can delay viral evolution of drug resistance for decades, it is associated with limitations, including an inability to eradicate the virus and a potential for adverse effects. Therefore, it is imperative to discover new HIV therapeutic modalities. In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to RNA Interference and Gene Delivery

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31394430
DOI: 10.1016/j.omtn.2019.07.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 11 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV TherapyPMID 31394430Read ↗

Antisense Oligonucleotide-Based Therapy of Viral InfectionsSemantic proximity Read ↗

Investigation of the Activity of LNA-Modified Phosphorothioate Oligonucleotides Against HIV-1Semantic proximity Read ↗

Inhibition of SARS-CoV-2 Infection in Human Airway Epithelium with a Xeno-Nucleic Acid AptamerSemantic proximity Read ↗

Substrate and target selectivity of 4′-fluoroadenosine against viral and host polymerasesSemantic proximity Read ↗

HIV-1 inactivation by nucleic acid aptamersSemantic proximity Read ↗

TAR decoys and trans-dominant gag mutant for HIV-1 gene therapy.Semantic proximity Read ↗

RNAi in Combination with a Ribozyme and TAR Decoy for Treatment of HIV Infection in Hematopoietic Cell Gene TherapySemantic proximity Read ↗

The Block-and-Lock Strategy for Human Immunodeficiency Virus Cure: Lessons Learned from Didehydro–Cortistatin ASemantic proximity Read ↗

A Lateral Flow Assay for Quantitative Detection of Amplified HIV-1 RNASemantic proximity Read ↗

6-Desfluoroquinolones as HIV-1 Tat-Mediated Transcription InhibitorsSemantic proximity Read ↗

Xeno-nucleic Acid (XNA) 2’-Fluoro-Arabino Nucleic Acid (FANA) Aptamers to the Receptor Binding Domain of SARS-CoV-2 S Protein Block ACE2 BindingSemantic proximity Read ↗

Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.