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Article

HIV-1 inactivation by nucleic acid aptamers

1 Jan 2006

Abstract excerpt

Although developments in small-molecule therapeutics for HIV-1 have been dramatic in recent years, the rapid selection of drug-resistant viral strains and the adverse side effects associated with long-term exposure to current treatments propel continued exploration of alternative anti-HIV-1 agents. Non-coding nucleic acids have emerged as potent inhibitors that dramatically suppress viral function both in vitro...

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Identifiers

PMID: 16146716
DOI: 10.2741/1782

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