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Keratin 17 identifies the most lethal molecular subtype of pancreatic cancer

2 Aug 2019

Abstract excerpt

Although the overall five-year survival of patients with pancreatic ductal adenocarcinoma (PDAC) is dismal, there are survival differences between cases with clinically and pathologically indistinguishable characteristics, suggesting that there are uncharacterized properties that drive tumor progression. Recent mRNA sequencing studies reported gene-expression signatures that define PDAC molecular subtypes that...

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PMID: 31375762
DOI: 10.1038/s41598-019-47519-4

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