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Article

IGHG1 Regulates Prostate Cancer Growth via the MEK/ERK/c-Myc Pathway

4 Jul 2019

Abstract excerpt

Increasing evidence indicates that immunoglobulins are important for the regulation of various cancers including prostate cancer (PCa). However, the underlying mechanisms of IgG regulated PCa development remain to be further explored. Here, we demonstrated that IgG1 heavy chain (IGHG1) was increased in tissues from PCa patients. Inhibition of IGHG1 by antibody blocking or genetic knockdown suppressed cell growth...

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Identifiers

PMID: 31355278
DOI: 10.1155/2019/7201562

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