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Article

Immunoglobulin G expression in carcinomas and cancer cell lines

2 May 2007

Abstract excerpt

The traditional view that immunoglobulin is produced only by differentiated B lymphocytes has been challenged as immunoglobulin genes have been found to be expressed in nonhematopoietic human cancer cells. However, this phenomenon has not been widely accepted, and knowledge about this newly discovered concept is limited. In this study, we investigated the IgG1 heavy chain (IGHG1) constant region gene and IgG...

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PMID: 17475920
DOI: 10.1096/fj.07-8073com

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