Article
APOL1 renal-risk genotypes associate with longer hemodialysis survival in prevalent nondiabetic African American patients with end-stage renal disease.
Kidney international - 1 Aug 2016
Ma Lijun, Langefeld Carl D, Comeau Mary E, Bonomo Jason A, Rocco Michael V, Burkart John M, Divers Jasmin, Palmer Nicholette D, Hicks Pamela J, Bowden Donald W, Lea Janice P, Krisher Jenna O, Clay Margo J, Freedman Barry I
Abstract excerpt
Relative to European Americans, evidence supports that African Americans with end-stage renal disease (ESRD) survive longer on dialysis. Renal-risk variants in the apolipoprotein L1 gene (APOL1), associated with nondiabetic nephropathy and less subclinical atherosclerosis, may contribute to dialysis outcomes. Here, APOL1 renal-risk variants were assessed for association with dialytic survival in 450 diabetic and...
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