Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in APOL1 associates with younger age at hemodialysis initiation.

Journal of the American Society of Nephrology : JASN - 1 Nov 2011

Kanji Zahra, Powe Camille E, Wenger Julia B, Huang Chunmei, Ankers Elizabeth, Sullivan Dorothy A, Collerone Gina, Powe Neil R, Tonelli Marcello, Bhan Ishir, Bernhardy Andrea J, Dibartolo Salvatore, Friedman David, Genovese Giulio, Pollak Martin R, Thadhani Ravi

Abstract excerpt

African Americans have a markedly higher incidence of ESRD compared with other racial groups. Two variants in the APOL1 gene, to date observed only among individuals of recent African ancestry, associate with increased risk for renal disease among African Americans. Here, we investigated whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein L1
Share to Apolipoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black or African American

Share to Incidence

Share to Kidney Failure, Chronic

Share to Lipoproteins, HDL

Share to Renal Dialysis

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 21997398
DOI: 10.1681/ASN.2010121234
PMCID: PMC3231784

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21997398-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in APOL1 associates with younger age at hemodialysis initiation.PMID 21997398Read ↗

APOL1-Associated Kidney Disease in BrazilSemantic proximity Read ↗

APOL1 allelic variants are associated with lower age of dialysis initiation and thereby increased dialysis vintage in African and Hispanic Americans with non-diabetic end-stage kidney disease.Semantic proximity Read ↗

APOL1 renal-risk genotypes associate with longer hemodialysis survival in prevalent nondiabetic African American patients with end-stage renal disease.Semantic proximity Read ↗

APOL1 risk variants and death among African American hemodialysis patients: survival of the fittest?Semantic proximity Read ↗

APOL1 variants associate with increased risk of CKD among African Americans.Semantic proximity Read ↗

Hemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study.Semantic proximity Read ↗

The evolving science of apolipoprotein-L1 and kidney disease.Semantic proximity Read ↗

African American living-kidney donors should be screened for APOL1 risk alleles.Semantic proximity Read ↗

End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.Semantic proximity Read ↗

Testing for High-Risk APOL1 Alleles in Potential Living Kidney Donors.Semantic proximity Read ↗

Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.Semantic proximity Read ↗

Clinical phenotype of APOL1 nephropathy in young relatives of patients with end-stage renal disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.