Article
Role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain.
PloS one - 1 Jan 2013
Helmer Rebecca A, Foreman Oded, Dertien Janet S, Panchoo Marlyn, Bhakta Suhani M, Chilton Beverly S
Abstract excerpt
HLTF participates in transcription, chromatin remodeling, DNA damage repair, and tumor suppression. Aside from being expressed in mouse brain during embryonic and postnatal development, little is known about Hltf's functional importance. Splice variant quantification of wild-type neonatal (6-8 hour postpartum) brain gave a ratio of 5:1 for Hltf isoform 1 (exons 1-25) to isoform 2 (exons 1-21 with exon 21 extended...
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