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Article

Polymorphisms in the NQO1, GSTT and GSTM genes are associated with coronary heart disease and biomarkers of oxidative stress.

Mutation research - 31 Mar 2009

Martin Nicholas J, Collier Abby C, Bowen Lance D, Pritsos Karen L, Goodrich Geoffrey G, Arger Kosta, Cutter Gary, Pritsos Chris A

Abstract excerpt

It was hypothesized that the presence of genetic polymorphisms that decrease activity of the detoxification enzymes glutathione-S-transferase (GST) and quinone oxido-reductase (NQO1) may contribute to heart disease and affect biomarkers of coronary health and oxidative stress. Sixty-seven patients with angiographically confirmed coronary heart disease (CHD) and 63 healthy controls were genotyped for polymorphisms...

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Source

Identifiers

PMID: 18950733
DOI: 10.1016/j.mrgentox.2008.09.009

Genes

NQO1
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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