Article

Oxidative Stress and DNA Damage Biomarkers in Heart Failure: A Systematic Review and Meta-Analysis

2025-10-02

Abstract excerpt

<h4>Background: </h4> Oxidative stress is a key driver of heart failure (HF) pathophysi-ology, promoting myocardial injury, inflammation, and remodeling. Alt-hough numerous biomarkers of oxidative stress and DNA damage have been investigated in HF, their clinical relevance remains uncertain. This systematic review and meta-analysis aimed to evaluate alterations in these biomarkers in HF patients compared to health...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 02da3926-3a8c-5ea7-9753-a3257182e290
DOI: 10.20944/preprints202510.0095.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Oxidative Stress and DNA Damage Biomarkers in Heart Failure: A Systematic Review and Meta-AnalysisDOI 10.20944/preprints202510.0095.v1Read

Role of Oxidative DNA Damage and Repair in Atrial Fibrillation and Ischemic Heart DiseaseSemantic proximity Read

Mitochondrial Reactive Oxygen Species Dysregulation in Heart Failure with Preserved Ejection Fraction: A Fraction of the WholeSemantic proximity Read

Molecular insights into mitoepigenetic stress response signaling in age-associated cardiovascular disease riskSemantic proximity Read

Oxidative Stress: Mechanisms, Quantification and its role in human agingSemantic proximity Read

Oxidative DNA Damage and Arterial Hypertension in Light of Current ESC GuidelinesSemantic proximity Read

Genome instability in peripheral blood lymphocytes of patients with heart failure and reduced ejection fractionSemantic proximity Read

Mitochondrial respiratory dysfunctions of blood mononuclear cells link with cardiac disturbance in patients with early-stage heart failureSemantic proximity Read

Redox Imbalance and Genetic Mutations in Heart Failure: Synergistic Mechanisms and Therapeutic Strategies.Semantic proximity Read

Genetic Evidence Linking Inflammatory Cytokines and Blood Metabolites to Heart Failure Risk.Semantic proximity Read

DNA damage, nucleolar stress and dysregulated energy metabolism as mechanisms of multimorbidity in cardiovascular diseaseSemantic proximity Read

GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytesSemantic proximity Read

Joint Application of Multiple Inflammatory Cytokines in Development of Heart FailureSemantic proximity Read