Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between GSTM1 genotype and IL-6 on mortality in older adults: results from the ilSIRENTE study.

Cytokine - 1 Mar 2011

Onder Graziano, Capoluongo Ettore, Giovannini Silvia, Concolino Paola, Russo Andrea, Liperoti Rosa, Bernabei Roberto, Landi Francesco

Abstract excerpt

BACKGROUND AND AIMS: The inflammatory process is related to oxidative stress and inflammation was proven to be a strong determinant of the aging process and to ultimately lead to death. The aim of the present study was to assess if, in a population of older adults, the effect of antioxidant genes GSTM1 and GSTT1 genotypes on mortality may differ depending on levels of inflammation. METHODS: Data are from 353...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to Inflammation

Share to Interleukin-6

Share to Kaplan-Meier Estimate

Share to Survival Rate

Source

Identifiers

PMID: 21169033
DOI: 10.1016/j.cyto.2010.11.020

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between GSTM1 genotype and IL-6 on mortality in older adults: results from the ilSIRENTE study.PMID 21169033Read ↗

Associations of the -174 G/C interleukin-6 gene promoter polymorphism with serum interleukin 6 and mortality in the elderly.Semantic proximity Read ↗

Effect of interleukin-6 polymorphisms on human longevity: a systematic review and meta-analysis.Semantic proximity Read ↗

The IL-6 -174G>C polymorphism is associated with cardiovascular diseases and mortality in 80-year-old humans.Semantic proximity Read ↗

Inflamm-Aging, Cytokines and Aging: State of the Art, New Hypotheses on the Role of Mitochondria and New Perspectives from Systems BiologySemantic proximity Read ↗

Interaction between and impact of IL-6 genotype and alpha-tocopherol levels on periodontal condition in aging individuals.Semantic proximity Read ↗

Distributions of interleukin-6 (IL-6) promoter and metallothionein 2A (MT2A) core promoter region gene polymorphisms and their associations with aging in Turkish population.Semantic proximity Read ↗

Cumulative Inflammatory Load Is Associated with Short Leukocyte Telomere Length in the Health, Aging and Body Composition StudySemantic proximity Read ↗

Glutathione Transferase P1 Polymorphism Might Be a Risk Determinant in Heart FailureSemantic proximity Read ↗

Association of longevity with TNF-α G308A and IL-6 G174C polymorphic inflammatory biomarkers in Caucasians: a meta-analysis.Semantic proximity Read ↗

Chronic inflammation as a determinant of future aging phenotypes.Semantic proximity Read ↗

Association of xenobiotic-metabolizing enzymes (GSTM1 and GSTT 1), and pro-inflammatory cytokines (TNF-α and IL-6) genetic polymorphisms with non-alcoholic fatty liver disease.Semantic proximity Read ↗

Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.