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A Physical Interaction Network of Dengue Virus and Human Proteins

13 Sept 2011

Abstract excerpt

Dengue virus (DENV), an emerging mosquito-transmitted pathogen capable of causing severe disease in humans, interacts with host cell factors to create a more favorable environment for replication. However, few interactions between DENV and human proteins have been reported to date. To identify DENV-human protein interactions, we used high-throughput yeast two-hybrid assays to screen the 10 DENV proteins against a...

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PMID: 21911577
DOI: 10.1074/mcp.m111.012187

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