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Article

Glial α‐synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo

3 Jul 2019

Abstract excerpt

α-Synucleinopathies are neurodegenerative diseases that are characterized pathologically by α-synuclein inclusions in neurons and glia. The pathologic contribution of glial α-synuclein in these diseases is not well understood. Glial α-synuclein may be of particular importance in multiple system atrophy (MSA), which is defined pathologically by glial cytoplasmic α-synuclein inclusions. We have previously described...

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PMID: 31267577
DOI: 10.1002/glia.23671

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