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Article

Parkinson's disease risk genes act in glia to control neuronal α-synuclein toxicity.

Neurobiology of disease - 1 Nov 2021

Olsen Abby L, Feany Mel B

Abstract excerpt

Idiopathic Parkinson's disease is the second most common neurodegenerative disease and is estimated to be approximately 30% heritable. Genome wide association studies have revealed numerous loci associated with risk of development of Parkinson's disease. The majority of genes identified in these studies are expressed in glia at either similar or greater levels than their expression in neurons, suggesting that...

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Identifiers

PMID: 34390834
DOI: 10.1016/j.nbd.2021.105482
PMCID: PMC8502212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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