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Article

The Role of Dimensionality in Understanding Granuloma Formation

14 Nov 2018

Abstract excerpt

Within the first 2–3 months of a Mycobacterium tuberculosis (Mtb) infection, 2–4 mm spherical structures called granulomas develop in the lungs of the infected hosts. These are the hallmark of tuberculosis (TB) infection in humans and non-human primates. A cascade of immunological events occurs in the first 3 months of granuloma formation that likely shapes the outcome of the infection. Understanding the main...

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PMID: 31258937
DOI: 10.3390/computation6040058

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