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Characterization of bidirectional gene pairs in The Cancer Genome Atlas (TCGA) dataset

17 Jun 2019

Abstract excerpt

The "bidirectional gene pair" indicates a particular head-to-head gene organization in which transcription start sites of two genes are located on opposite strands of genomic DNA within a region of one kb. Despite bidirectional gene pairs are well characterized, little is known about their expression profiles and regulation features in tumorigenesis. We used RNA-seq data from The Cancer Genome Atlas (TCGA)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31245179
DOI: 10.7717/peerj.7107

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