Article
Competing endogenous RNA network analysis identifies critical genes among the different breast cancer subtypes.
Oncotarget - 7 Feb 2017
Chen Juan, Xu Juan, Li Yongsheng, Zhang Jinwen, Chen Hong, Lu Jianping, Wang Zishan, Zhao Xueying, Xu Kang, Li Yixue, Li Xia, Zhang Yan
Abstract excerpt
Although competing endogenous RNAs (ceRNAs) have been implicated in many solid tumors, their roles in breast cancer subtypes are not well understood. We therefore generated a ceRNA network for each subtype based on the significance of both, positive co-expression and the shared miRNAs, in the corresponding subtype miRNA dys-regulatory network, which was constructed based on negative regulations between...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.