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Transcriptomic analysis of enteropathy in Zambian children with severe acute malnutrition

20 Jun 2019

Abstract excerpt

BACKGROUND: Children with severe acute malnutrition (SAM), with or without diarrhoea, often have enteropathy, but there are few molecular data to guide development of new therapies. We set out to determine whether SAM enteropathy is characterised by specific transcriptional changes which might improve understanding or help identify new treatments. METHODS: We collected intestinal biopsies from children with SAM...

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PMID: 31229436
DOI: 10.1016/j.ebiom.2019.06.015

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