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Multi-omics, multi-tissue analysis reveal role of extracellular matrix remodeling and lipid transport dysfunction in edematous malnutrition (kwashiorkor)

2025-12-16

Abstract excerpt

<title>Abstract</title> <p>Edematous malnutrition, aka kwashiorkor, is a phenotype of severe malnutrition whose pathophysiology remains poorly understood. In this case-control study, we employed plasma lipidomics, metabolomics, and proteomics, urine metabolomics and gut microbiome profiling to delineate molecular pathways specific to kwashiorkor in 60 children aged 6–59 months from Niger compared to marasmus (n =...

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Literature Corpus work
bfa666d7-57bd-5049-8d8c-1f824dfa1dfd
DOI
10.21203/rs.3.rs-8320069/v1
Open publication

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Multi-omics, multi-tissue analysis reveal role of extracellular matrix remodeling and lipid transport dysfunction in edematous malnutrition (kwashiorkor)DOI 10.21203/rs.3.rs-8320069/v1
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