Article
Characterizing the metabolic phenotype of intestinal villus blunting in Zambian children with severe acute malnutrition and persistent diarrhea.
PloS one - 1 Jan 2018
Farràs Marta, Chandwe Kanta, Mayneris-Perxachs Jordi, Amadi Beatrice, Louis-Auguste John, Besa Ellen, Zyambo Kanekwa, Guerrant Richard, Kelly Paul, Swann Jonathan Richard
Abstract excerpt
BACKGROUND: Environmental enteric dysfunction (EED) is widespread throughout the tropics and in children is associated with stunting and other adverse health outcomes. One of the hallmarks of EED is villus damage. In children with severe acute malnutrition (SAM) the severity of enteropathy is greater and short term mortality is high, but the metabolic consequences of enteropathy are unknown. Here, we characterize...
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