Article
Interactions between fecal gut microbiome, enteric pathogens, and energy regulating hormones among acutely malnourished rural Gambian children.
EBioMedicine - 1 Nov 2021
Nabwera Helen M, Espinoza Josh L, Worwui Archibald, Betts Modupeh, Okoi Catherine, Sesay Abdul K, Bancroft Rowan, Agbla Schadrac C, Jarju Sheikh, Bradbury Richard S, Colley Mariama, Jallow Amadou T, Liu Jie, Houpt Eric R, Prentice Andrew M, Antonio Martin, Bernstein Robin M, Dupont Christopher L, Kwambana-Adams Brenda A
Abstract excerpt
BACKGROUND: The specific roles that gut microbiota, known pathogens, and host energy-regulating hormones play in the pathogenesis of non-edematous severe acute malnutrition (marasmus SAM) and moderate acute malnutrition (MAM) during outpatient nutritional rehabilitation are yet to be explored. METHODS: We applied an ensemble of sample-specific (intra- and inter-modality) association networks to gain deeper...
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