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Article

Genetic variation in environmental enteropathy and stunting in Zambian children: A pilot genome wide association study using the H3Africa chip.

PloS one - 1 Jan 2023

Mweetwa Monica N, Haritunians Talin, Dube Shishir, Chandwe Kanta, Amadi Beatrice, Zyambo Kanekwa, Liu Ta-Chiang, McGovern Dermot, Kelly Paul

Abstract excerpt

PURPOSE: Stunting is known to be heavily influenced by environmental factors, so the genetic contribution has received little attention. Here we report an exploration of genetic influences in stunted Zambian children with environmental enteropathy. METHOD: Children with stunting (LAZ < -2) were enrolled and given nutritional therapy. Those that were non-responsive to therapy were designated as cases, and children...

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PMID: 37756315
DOI: 10.1371/journal.pone.0291311
PMCID: PMC10529557

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