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Carriage of Shiga toxin phage profoundly affects Escherichia coli gene expression and carbon source utilization

17 Jun 2019

Abstract excerpt

BACKGROUND: Enterohemorrhagic Escherichia coli (E. coli) are intestinal pathogenic bacteria that cause life-threatening disease in humans. Their cardinal virulence factor is Shiga toxin (Stx), which is encoded on lambdoid phages integrated in the chromosome. Stx phages can infect and lysogenize susceptible bacteria, thus either increasing the virulence of already pathogenic bacterial hosts or transforming...

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PMID: 31208335
DOI: 10.1186/s12864-019-5892-x

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