Article
Escherichia coli O157:H7 strains harbor at least three distinct sequence types of Shiga toxin 2a-converting phages.
BMC genomics - 29 Sept 2015
Yin Shuang, Rusconi Brigida, Sanjar Fatemeh, Goswami Kakolie, Xiaoli Lingzi, Eppinger Mark, Dudley Edward G
Abstract excerpt
BACKGROUND: Shiga toxin-producing Escherichia coli O157:H7 is a foodborne pathogen that causes severe human diseases including hemolytic uremic syndrome (HUS). The virulence factor that mediates HUS, Shiga toxin (Stx), is encoded within the genome of a lambdoid prophage. Although draft sequences are publicly available for a large number of E. coli O157:H7 strains, the high sequence similarity of stx-converting...
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