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RNA-seq analysis of the influence of anaerobiosis and FNR on Shigella flexneri

6 Jun 2014

Abstract excerpt

BACKGROUND: Shigella flexneri is an important human pathogen that has to adapt to the anaerobic environment in the gastrointestinal tract to cause dysentery. To define the influence of anaerobiosis on the virulence of Shigella, we performed deep RNA sequencing to identify transcriptomic differences that are induced by anaerobiosis and modulated by the anaerobic Fumarate and Nitrate Reduction regulator, FNR....

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PMID: 24907032
DOI: 10.1186/1471-2164-15-438

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