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Identification and pathogenomic analysis of an Escherichia coli strain producing a novel Shiga toxin 2 subtype.

Scientific reports - 30 Apr 2018

Bai Xiangning, Fu Shanshan, Zhang Ji, Fan Ruyue, Xu Yanmei, Sun Hui, He Xiaohua, Xu Jianguo, Xiong Yanwen

Abstract excerpt

Shiga toxin (Stx) is the key virulent factor in Shiga toxin-producing Escherichia coli (STEC). To date, three Stx1 subtypes and seven Stx2 subtypes have been described in E. coli, which differed in receptor preference and toxin potency. Here, we identified a novel Stx2 subtype designated Stx2h in E. coli strains isolated from wild marmots in the Qinghai-Tibetan plateau, China. Stx2h shares 91.9% nucleic acid...

Topics

Animals
China
Chlorocebus aethiops
Escherichia coli Infections
Genotype
Humans
Marmota
Shiga Toxin 2
Shiga-Toxigenic Escherichia coli
Vero Cells
Virulence Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29712985
DOI: 10.1038/s41598-018-25233-x
PMCID: PMC5928088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-29712985-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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