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Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia

21 Sept 2017

Abstract excerpt

Prevotella intermedia, a major periodontal pathogen, is increasingly implicated in human respiratory tract and cystic fibrosis lung infections. Nevertheless, the specific mechanisms employed by this pathogen remain only partially characterized and poorly understood, largely due to its total lack of genetic accessibility. Here, using Single Molecule, Real-Time (SMRT) genome and methylome sequencing, bisulfite...

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PMID: 28934361
DOI: 10.1371/journal.pone.0185234

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