Sex in basic research: concepts in the cardiovascular field.

doi:10.1093/cvr/cvx066

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Sex in basic research: concepts in the cardiovascular field.

Cardiovascular research - 1 Jun 2017

Ventura-Clapier Renée, Dworatzek Elke, Seeland Ute, Kararigas Georgios, Arnal Jean-Francois, Brunelleschi Sandra, Carpenter Thomas C, Erdmann Jeanette, Franconi Flavia, Giannetta Elisa, Glezerman Marek, Hofmann Susanna M, Junien Claudine, Katai Miyuki, Kublickiene Karolina, König Inke R, Majdic Gregor, Malorni Walter, Mieth Christin, Miller Virginia M, Reynolds Rebecca M, Shimokawa Hiroaki, Tannenbaum Cara, D'Ursi Anna Maria, Regitz-Zagrosek Vera

Abstract excerpt

Women and men, female and male animals and cells are biologically different, and acknowledgement of this fact is critical to advancing medicine. However, incorporating concepts of sex-specific analysis in basic research is largely neglected, introducing bias into translational findings, clinical concepts and drug development. Research funding agencies recently approached these issues but implementation of policy...

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PMID: 28472454
DOI: 10.1093/cvr/cvx066

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