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Article

CircRNA-9119 suppresses poly I:C induced inflammation in Leydig and Sertoli cells via TLR3 and RIG-I signal pathways

13 Jun 2019

Abstract excerpt

BACKGROUND: Circular RNAs (circRNAs) contribute to the epigenetic modulation of pathological and physiological conditions. The understanding of the impact of circRNAs on generation of testicular inflammatory reactions is insufficient. METHODS: Our research adopted a poly I:C-triggered testicular inflammation murine model and cell assays. RESULTS: Microarray data and quantitative evaluation revealed the elevation...

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PMID: 31195953
DOI: 10.1186/s10020-019-0094-1

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