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Modeling primitive and definitive erythropoiesis with induced pluripotent stem cells

30 Jan 2024

Abstract excerpt

ABSTRACT: During development, erythroid cells are produced through at least 2 distinct hematopoietic waves (primitive and definitive), generating erythroblasts with different functional characteristics. Human induced pluripotent stem cells (iPSCs) can be used as a model platform to study the development of red blood cells (RBCs) with many of the differentiation protocols after the primitive wave of hematopoiesis....

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PMID: 38290102
DOI: 10.1182/bloodadvances.2023011708

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