Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 at the Crossroads between Different Types of HDAC Inhibitor-Mediated Cancer Cell Death

15 May 2019

Abstract excerpt

Cancer is a complex genetic and epigenetic-based disease that has developed an armada of mechanisms to escape cell death. The deregulation of apoptosis and autophagy, which are basic processes essential for normal cellular activity, are commonly encountered during the development of human tumors. In order to assist the cancer cell in defeating the imbalance between cell growth and cell death, histone deacetylase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Epigenetics and DNA Methylation
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31096697
DOI: 10.3390/ijms20102415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 at the Crossroads between Different Types of HDAC Inhibitor-Mediated Cancer Cell DeathPMID 31096697Read ↗

Epigenetic Targeting of Autophagy via HDAC Inhibition in Tumor Cells: Role of p53Semantic proximity Read ↗

Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced AutophagySemantic proximity Read ↗

Autophagic and Apoptotic Effects of HDAC Inhibitors on Cancer CellsSemantic proximity Read ↗

Dysregulation of histone deacetylases in carcinogenesis and tumor progression: a possible link to apoptosis and autophagySemantic proximity Read ↗

HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor EntitiesSemantic proximity Read ↗

Interplay between histone deacetylases and autophagy ‐ from cancer therapy to neurodegenerationSemantic proximity Read ↗

Histone Deacetylase Inhibitors in Programmed Cell Death and Cancer TherapySemantic proximity Read ↗

p53-Mediated Molecular Control of Autophagy in Tumor CellsSemantic proximity Read ↗

Histone-Deacetylase Inhibitors for the Treatment of CancerSemantic proximity Read ↗

P53-regulated autophagy and its impact on drug resistance and cell fateSemantic proximity Read ↗

Mechanisms of Selective Anticancer Action of Histone Deacetylase InhibitorsSemantic proximity Read ↗

Interplay between apoptosis and autophagy, a challenging puzzle: New perspectives on antitumor chemotherapiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.