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p53-Mediated Molecular Control of Autophagy in Tumor Cells

21 Mar 2018

Abstract excerpt

Autophagy is an indispensable mechanism of the eukaryotic cell, facilitating the removal and renewal of cellular components and thereby balancing the cell's energy consumption and homeostasis. Deregulation of autophagy is now regarded as one of the characteristic key features contributing to the development of tumors. In recent years, the suppression of autophagy in combination with chemotherapeutic treatment has...

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PMID: 29561758
DOI: 10.3390/biom8020014

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